Publications & Posters
Scholary publications
March 2018
Gordon Research Conference
Discovery of an isoform-specific inhibitor of TGFβ1 activation using antibody display technology
Spinal Muscular Atrophy
Apitegromab
February 2018
Scientific Reports
Blocking extracellular activation of myostatin as a strategy for treating muscle wasting
Platform
January 2018
The Embo Journal
Tolloid cleavage activates latent GDF8 by priming the pro-complex for dissociation.
Spinal Muscular Atrophy
Apitegromab
January 2018
European SMA Research Congress
Inhibition of myostatin activation by SRK-015 promotes muscle strength in a multiple mouse models of SMA
Fibrosis
SRK-373
November 2017
ASN Kidney Week
A novel, highly specific TGFβ1 inhibiting antibody demonstrates antifibrotic activity without cardiotoxicity
Fibrosis
SRK-373
August 2017
Gordon Research Conference