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Scholarly publications

Spinal Muscular Atrophy

Apitegromab

July 2024

Frontiers in Neurology

Long-term efficacy, safety, and patient-reported outcomes of apitegromab in patients with spinal muscular atrophy: results from the 36-month TOPAZ study

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Fibrosis

SRK-373

July 2024

Science Signaling

An antibody that inhibits TGFβ1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis

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Spinal Muscular Atrophy

Apitegromab

February 2024

Neurology

Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3

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Platform

November 2022

Antibodies

Risk-Based Control Strategies of Recombinant Monoclonal Antibody Charge Variants

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Spinal Muscular Atrophy

Apitegromab

July 2021

International Journal of Toxicology

Preclinical Safety Assessment and Toxicokinetics of Apitegromab, an Antibody Targeting Proforms of Myostatin for the Treatment of Muscle-Atrophying Disease

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Spinal Muscular Atrophy

Apitegromab

May 2021

Advances in Therapy

A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy

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