Growth Factor Activation

A New Way to Target Disease

Traditional therapeutic approaches directly target a growth factor or its receptor everywhere in the body, not only shutting down its harmful function in disease, but also potentially causing undesirable side effects arising from the inherent biology of growth factors. Individual growth factors occur as members of larger families of structurally related proteins and a single growth factor can lead to a different biological effect in different tissues. Our medicines target growth factors in their latent, inactive forms to selectively and locally modulate growth factor activity.

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