PLATFORM
Published Research

Mi LZ, Brown CT, Tian Y, Le VQ, Walz T Springer TA. Structure of bone morphogenetic protein 9 procomplex. 2015. Proc. Natl. Acad. Sci. USA
112(12):3710-5

Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagerorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI. Hematopoietic stem cell triggers dynamic remodeling of the perivascular niche. 2015. Cell 160 (1-2):241-52

Mosimann C, Panakova D, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, Zon Li. Chamber identity programs drive early functional partitioning of the heart. 2015. Nat. Commun. 6:8146

Dong X, Hudson NE, Lu C, Springer TA. Structural determinants of integrin β-subunit specificity for latent TGF-β. 2014. Nat. Struct. Mol. Biol. 21(12):1091-6

Bowman TV, Trompouki E, Zon LI. Linking hematopoietic regeneration to developmental signaling pathways: a story of BMP and Wnt. 2012. Cell Cycle 11(3):424-5

Lengerke C, Schmitt S, Bowman TV, Jang IH, Maouche-Chretien L, McKinney-Freeman S, Davidson AJ, Hammerschmidt M, Rentzsch F, Green JB, Zon LI, Daley GQ. BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. 2008. Cell Stem Cell 2(1):72-82

Schürpf T, Springer TA. Regulation of integrin affinity on cell surfaces. 2011. EMBO J. 30(23):4712-27

Shi M, Zhu J, Wang R, Chen X, Mi L, Walz T, Springer TA. Latent TGF-β structure and activation. 2011. Nature 474(7351):343-9

Trompouki E, Bowman TV, Lawton LN, Fan ZP, Wu DC, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand EM, Mosimann C, Heffner GC, Daley GQ, Paulson RF, Young RA, Zon LI. Lineage regulators direct BMP and Wnt pathways to cell specific programs during differentiation and regeneration. 2011. Cell 147(3):577-89

Wang R, Zhu J, Dong X, Shi M, Lu C, Springer TA. GARP regulates the bioavailability and activation of TGFβ. 2012. Mol. Biol. Cell. 23(6):1129-39

Xu C, Tabebordbar M, Iovino S, Ciarlo CA, Liu Z, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. 2013. Cell 155(4), 909-921

Yu Y, Schürpf T, Springer TA. How Natalizumab Binds and Antagonizes α4 Integrins. 2013. J. Biol. Chem. 288(45): 32314-32325